Adenovirus protocol Download For most serotypes, adenovirus infection is mediated by the high-affinity binding of the fiber-knob region to a receptor of target cell, named as the coxsackie-Ad receptor (CAR) [17]. Upon attachment, interaction between the penton-base Arg-Gly-Asp (RGD) and cellular αv integrins, which can stimulate actin polymerization, leads to internalization of the virus into […]
Category Archives: adenovirus
Adenovirus protocol Download Adenovirus is a non-enveloped, 90-100 nm diameter virus presenting icosahedral symmetry (Figure1A). Human adenovirus, containing a linear, double-stranded DNA genome, which is approximately 36kb, is wrapped in a histone-like protein and has two inverted terminal repeats (ITRs) of 50-200 bp, which act as origins of replication, accompanied by a complex series of […]
Adenovirus Knowledge base What is Adenovirus vector? Adenovirus (AdV) is a member of the family Adenoviridae, whose name derives from their initial isolation from human adenoids in 1953 [1]. It is a medium-sized (90-100nm) and non-enveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. Read More Adenovirus Gene Therapy Review Adenovirus has been […]
COVID-19 vaccine development protocol: PSV Based Neutralization Assay Table of Contents Abstract The vaccine helps to provoke the immune system and is an efficacious means for disease prevention and treatment. At this particular time of the COVID-19 outbreak, the vaccine for COVID-19 is urgently needed to save tens of thousands of people’s lives. Here we […]
GeneMedi Lab offer a variety of Pre-made and Pre-packaging control adenovirus vector (serotype 5 adenoviral vector, Ad5) particleswith different fluorescent labels (such as GFP, RFP, YFP, luciferase, zsgreen, mCherry and so on), GeneMedi’s adenoviral vector system drived by various promoters (such as CMV, CAG, U6, syn, TBG and cTNT etc.). Our ready-to-use control adenovirus vectors […]
