Diagnostic antibodies and antigens for kidney function (renal damages) testing: Beta-2 microglobulin (B2M), Cystatin C (CYSC), Neutrophil gelatinase-associated lipocalin (NGAL), Alpha-1-microglobulin (A1M)

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The kidneys are important to filter wastes and excess fluids from the blood and excreted in urine. Chronic kidney disease steadily loss the kidney function and fail to filter the waste in the body. The chronic kidney disease (CKD) includes advanced stage of renal parenchyma damage and the loss of functional nephrons. The loss of functional nephrons induces several molecular and cellular events, which leads to the development of renal lesions. The chronic kidney disease disperses the podocytes from basal membrane and excrete in the urine, therefore the diagnosis usually made with the serum proteins (creatinine) and blood urea (sCr). The early diagnosis of this disease is an important step to prevent the CKD. Biomarker such as Cystatin C (CYSC) Neutrophil gelatinase-associated lipocalin (NGAL),Beta-2 microglobulin (B2M),Alpha-1-microglobulin (A1M) and so on are suitable for monitoring CKD at early stages. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Beta-2 microglobulin (B2M)

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Human
Beta-2 microglobulin
GMP-h-B2M-Ag01
Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation
GMP-h-B2M-Ab01;GMP-h-B2M-Ab02:Anti-Human B2M mouse monoclonal antibody (mAb)
Human Beta-2 microglobulin (B2M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Beta-2 microglobulin (B2M) antibodies in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.

Cystatin C (CYSC)

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Human
Cystatin C
GMP-h-CYSC-Ag01
Cystatin C (CYSC) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CYSC level test of Kidney function (renal damages) (kidney function (renal damages)) and related syndrome evaluation
GMP-h-CYSC-Ab01;GMP-h-CYSC-Ab02:Anti-Human CYSC mouse monoclonal antibody (mAb)
Human Cystatin C (CYSC) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Cystatin C (CYSC) antibodies in CYSC level test of Kidney function (renal damages) (kidney function (renal damages)) and related syndrome evaluation.

Neutrophil gelatinase-associated lipocalin (NGAL)

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Human
Neutrophil gelatinase-associated lipocalin
GMP-h-NGAL-Ag01
Neutrophil gelatinase-associated lipocalin (NGAL) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NGAL level test of Kidney function (renal damages) (kidney injury) and related syndrome evaluation
GMP-h-NGAL-Ab01;GMP-h-NGAL-Ab02:Anti-Human NGAL mouse monoclonal antibody (mAb)
Human Neutrophil gelatinase-associated lipocalin (NGAL) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Neutrophil gelatinase-associated lipocalin (NGAL) antibodies in NGAL level test of Kidney function (renal damages) (kidney injury) and related syndrome evaluation.

Alpha-1-microglobulin (A1M)

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Alpha-1-microglobulin
GMP-h-A1M-Ag01
Alpha-1-microglobulin (A1M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation
GMP-h-A1M-Ab01;GMP-h-A1M-Ab02:Anti-Human A1M mouse monoclonal antibody (mAb)
Human Alpha-1-microglobulin (A1M) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Alpha-1-microglobulin (A1M) antibodies in A1M level test of Kidney function (renal damages) (Proteinuria, preeclampsia,) and related syndrome evaluation.