Immunoglobulin Fc receptor recombinant protein for antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay) to evaluate functional ADCC, ADCP, Fc Receptor blocking, and Fc receptor phagocytosis

Full product list of Fc receptor (FcR) and immunoglobulin

GeneMedi provides various Fc receptor (FcR), including FcγRI (CD64), FcγRIIA (CD32a), FcγRIIB (CD32b), FcγRIIC (CD32c), FcγRIIIA (CD16a), FcγRIIIB (CD16b), FcγRIII(CD16), FcγRIV, FcRn, TRIM21, FcRL1, FcRL4, FcRL5, FcαRI (CD89), PolyIgR, Fcα/uR (CD351), FcuR, FcεRI, FcεRII (CD23) in human, Cynomolgus/ Rhesus macaque, or mouse. Historically, these receptors have been classified based on their affinity for specific immunoglobulin. The FcR is expressed on many immune cells and binds to the specific immunoglobulin (IgG, IgA, IgM, IgE, ), then modulating the immune response. The FcR is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive Elisa, SRP or BLI) plays a vital role in the development of therapeutic antibodies.

Fc gamma receptor I (FcγRI, CD64)

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GMP-BioFcR-ag-001-2:Human Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated)
Fc gamma receptor I (FcγRI, CD64)
Human
IgG1, IgG3, IgG4
GMP-BioFcR-ag-002-2:Cynomolgus/ Rhesus macaque Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated)
Fc gamma receptor I (FcγRI, CD64)
Cynomolgus/ Rhesus macaque
IgG1, IgG3, IgG4
GMP-BioFcR-ag-003-2:Mouse Fc gamma receptor I (FcγRI, CD64) His+Avi (Biotinylated)
Fc gamma receptor I (FcγRI, CD64)
Mouse
IgG2a, IgG2b, IgG3

Fc gamma receptor II (FcγRII, CD32)

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GMP-BioFcR-ag-004-2:Human Fc gamma receptor IIA (FcγRIIA, CD32a, R167) His+Avi (Biotinylated)
Fc gamma receptor IIA (FcγRIIA, CD32a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-005-2:Human Fc gamma receptor IIA (FcγRIIA, CD32a, H167) His+Avi (Biotinylated)
Fc gamma receptor IIA (FcγRIIA, CD32a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-006-2:Human Fc gamma receptor IIA (FcγRIIA, CD32a, H131) His+Avi (Biotinylated)
Fc gamma receptor IIA (FcγRIIA, CD32a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-007-2:Human Fc gamma receptor IIA (FcγRIIA, CD32a, R131) His+Avi (Biotinylated)
Fc gamma receptor IIA (FcγRIIA, CD32a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-008-2:Cynomolgus/ Rhesus macaque Fc gamma receptor IIA (FcγRIIA, CD32a) His+Avi (Biotinylated)
Fc gamma receptor IIA (FcγRIIA, CD32a)
Cynomolgus/ Rhesus macaque
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-009-2:Human Fc gamma receptor IIB (FcγRIIB, CD32b) His+Avi (Biotinylated)
Fc gamma receptor IIB (FcγRIIB, CD32b)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-010-2:Human Fc gamma receptor IIB (FcγRIIB, CD32b, I232) His+Avi (Biotinylated)
Fc gamma receptor IIB (FcγRIIB, CD32b)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-011-2:Human Fc gamma receptor IIB (FcγRIIB, CD32b, T232) His+Avi (Biotinylated)
Fc gamma receptor IIB (FcγRIIB, CD32b)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-012-2:Cynomolgus/ Rhesus macaque Fc gamma receptor IIB (FcγRIIB, CD32b) His+Avi (Biotinylated)
Fc gamma receptor IIB (FcγRIIB, CD32b)
Cynomolgus/ Rhesus macaque
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-013-2:Mouse Fc gamma receptor IIB (FcγRIIB, CD32b) His+Avi (Biotinylated)
Fc gamma receptor IIB (FcγRIIB, CD32b)
Mouse
IgG1, IgG2a, IgG2b, IgE
GMP-BioFcR-ag-014-2:Human Fc gamma receptor IIC (FcγRIIC, CD32c) His+Avi (Biotinylated)
Fc gamma receptor IIC (FcγRIIC, CD32c)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-015-2:Human Fc gamma receptor IIC (FcγRIIC, CD32c, Q13) His+Avi (Biotinylated)
Fc gamma receptor IIC (FcγRIIC, CD32c)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-016-2:Human Fc gamma receptor IIC (FcγRIIC, CD32c, stop13) His+Avi (Biotinylated)
Fc gamma receptor IIC (FcγRIIC, CD32c)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-017-2:Human Fc gamma receptor IIC (FcγRIIC, CD32c, Q57) His+Avi (Biotinylated)
Fc gamma receptor IIC (FcγRIIC, CD32c)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-018-2:Human Fc gamma receptor IIC (FcγRIIC, CD32c, X57) His+Avi (Biotinylated)
Fc gamma receptor IIC (FcγRIIC, CD32c)
Human
IgG1, IgG2, IgG3, IgG4

Fc gamma receptor III(FcγRIII, CD16)

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GMP-BioFcR-ag-019-2:Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, F176) His+Avi (Biotinylated)
Fc gamma receptor IIIA (FcγRIIIA, CD16a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-020-2:Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V176) His+Avi (Biotinylated)
Fc gamma receptor IIIA (FcγRIIIA, CD16a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-021-2:Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, F158) His+Avi (Biotinylated)
Fc gamma receptor IIIA (FcγRIIIA, CD16a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-022-2:Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated)
Fc gamma receptor IIIA (FcγRIIIA, CD16a)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-023-2:Human Fc gamma receptor IIIB (FcγRIIIB, CD16b, NA1) His+Avi (Biotinylated)
Fc gamma receptor IIIB (FcγRIIIB, CD16b)
Human
IgG1, IgG3
GMP-BioFcR-ag-024-2:Human Fc gamma receptor IIIB (FcγRIIIB, CD16b, NA2) His+Avi (Biotinylated)
Fc gamma receptor IIIB (FcγRIIIB, CD16b)
Human
IgG1, IgG3
GMP-BioFcR-ag-025-2:Cynomolgus/ Rhesus macaque Fc gamma receptor III(FcγRIII, CD16) His+Avi (Biotinylated)
Fc gamma receptor III(FcγRIII, CD16)
Cynomolgus/ Rhesus macaque
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-026-2:Mouse Fc gamma receptor III(FcγRIII, CD16) His+Avi (Biotinylated)
Fc gamma receptor III(FcγRIII, CD16)
Mouse
IgG1, IgG2a, IgG2b, IgE

Fc gamma receptor IV (FcγRIV, FcgR4)

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Principal antibody ligand
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GMP-BioFcR-ag-027-2:Mouse Fc gamma receptor (FcγRIV, FcgR4) His+Avi (Biotinylated)
Fc gamma receptor (FcγRIV)
Mouse
IgG2a, IgG2b, IgE

Neonatal Fc receptor (FcRn)

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GMP-BioFcR-ag-028-2:Human Neonatal Fc receptor (FcRn) His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-029-2:Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Cynomolgus/ Rhesus macaque
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-030-2:Mouse Neonatal Fc receptor (FcRn) His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Mouse
IgG1, IgG2a, IgG2b, IgG3
GMP-BioFcR-ag-031-2:Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-032-2:Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Cynomolgus/ Rhesus macaque
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-033-2:Mouse Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated)
Neonatal Fc receptor (FcRn)
Mouse
IgG1, IgG2a, IgG2b, IgG3

Tripartite Motif Containing 21 (TRIM21)

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GMP-BioFcR-ag-034-2:Human Tripartite Motif Containing 21 (TRIM21) His+Avi (Biotinylated)
Tripartite Motif Containing 21 (TRIM21)
Human
IgG1, IgG2, IgG3, IgG4
GMP-BioFcR-ag-035-2:Mouse Tripartite Motif Containing 21 (TRIM21) His+Avi (Biotinylated)
Tripartite Motif Containing 21 (TRIM21)
Mouse
IgM

Fc receptor-like protein (FCRL)

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GMP-BioFcR-ag-036-2:Human Fc receptor-like protein 1 (FCRL1) His+Avi (Biotinylated)
Fc receptor-like protein 1 (FCRL1)
Human
FcRL1 does not bind to the Fc portion of any Ig isotype (IgM, IgA, IgG1, IgG2, IgG3, and IgG4)
GMP-BioFcR-ag-037-2:Human Fc receptor-like protein 4 (FCRL4) His+Avi (Biotinylated)
Fc receptor-like protein 4 (FCRL4)
Human
IgG3, IgG4, IgA
GMP-BioFcR-ag-038-2:Human Fc receptor-like protein 5 (FCRL5) His+Avi (Biotinylated)
Fc receptor-like protein 5 (FCRL5)
Human
IgG1, IgG2, IgG3, IgG4

Fc alpha receptor I (FcαRI, CD89)

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Principal antibody ligand
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GMP-BioFcR-ag-039-2:Human Fc alpha receptor I (FcαRI, CD89) His+Avi (Biotinylated)
Fc alpha receptor I (FcαRI, CD89)
Human
IgA
GMP-BioFcR-ag-040-2:Mouse Fc alpha receptor I (FcαRI, CD89) His+Avi (Biotinylated)
Fc alpha receptor I (FcαRI, CD89)
Mouse
IgA

Polymeric immunoglobulin receptor (PolyIgR)

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Principal antibody ligand
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GMP-BioFcR-ag-041-2:Human Polymeric immunoglobulin receptor (PolyIgR) His+Avi (Biotinylated)
Polymeric immunoglobulin receptor (PolyIgR)
Human
IgA, IgM
GMP-BioFcR-ag-042-2:Mouse Polymeric immunoglobulin receptor (PolyIgR) His+Avi (Biotinylated)
Polymeric immunoglobulin receptor (PolyIgR)
Mouse
IgA, IgM

Fc alpha/mu receptor (Fcα/uR, CD351)

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GMP-BioFcR-ag-043-2:Human Fc alpha/mu receptor (Fcα/uR, CD351) His+Avi (Biotinylated)
Fc alpha/mu receptor (Fcα/uR, CD351)
Human
IgA, IgM
GMP-BioFcR-ag-044-2:Mouse Fc alpha/mu receptor (Fcα/uR, CD351) His+Avi (Biotinylated)
Fc alpha/mu receptor (Fcα/uR, CD351)
Mouse
IgA, IgM

Fc mu receptor (FcuR)

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Principal antibody ligand
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GMP-BioFcR-ag-045-2:Human Fc mu receptor (FcuR) His+Avi (Biotinylated)
Fc mu receptor (FcuR)
Human
IgM
GMP-BioFcR-ag-046-2:Mouse Fc mu receptor (FcuR) His+Avi (Biotinylated)
Fc mu receptor (FcuR)
Mouse
IgM

Fc epsilon receptor I (FcεRI)

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Principal antibody ligand
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GMP-BioFcR-ag-047-2:Human Fc epsilon receptor I (FcεRI) His+Avi (Biotinylated)
Fc epsilon receptor I (FcεRI)
Human
IgE
GMP-BioFcR-ag-048-2:Mouse Fc epsilon receptor I (FcεRI) His+Avi (Biotinylated)
Fc epsilon receptor I (FcεRI)
Mouse
IgE

Fc epsilon receptor II (FcεRII, CD23)

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Principal antibody ligand
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GMP-BioFcR-ag-049-2:Human Fc epsilon receptor II (FcεRII, CD23) His+Avi (Biotinylated)
Fc epsilon receptor II (FcεRII, CD23)
Human
IgE
GMP-BioFcR-ag-050-2:Mouse Fc epsilon receptor II (FcεRII, CD23) His+Avi (Biotinylated)
Fc epsilon receptor II (FcεRII, CD23)
Mouse
IgE

IgG

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Species
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Recombinant Human Fc Protein IgG1
IgG1
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgG1
IgG1
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgG1
IgG1
Mouse
Recombinant Human Fc Protein IgG2
IgG2
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgG2
IgG2
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgG2a
IgG2a
Mouse
Recombinant Mouse Fc Protein IgG2b
IgG2b
Mouse
Recombinant Human Fc Protein IgG3
IgG3
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgG3
IgG3
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgG3
IgG3
Mouse
Recombinant Human Fc Protein IgG4
IgG4
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgG4
IgG4
Cynomolgus/ Rhesus macaque

IgA

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Recombinant Human Fc Protein IgA1
IgA1
Human
Recombinant Human Fc Protein IgA2
IgA2
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgA
IgA
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgA
IgA
Mouse

IgM

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Recombinant Human Fc Protein IgM
IgM
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgM
IgM
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgM
IgM
Mouse

IgE

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Recombinant Human Fc Protein IgE
IgE
Human
Recombinant Cynomolgus/ Rhesus macaque Fc Protein IgE
IgE
Cynomolgus/ Rhesus macaque
Recombinant Mouse Fc Protein IgE
IgE
Mouse
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