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Introduction to Adenovirus Amplification and purification Service
The adenoviral vectors provided by Genemedi are based on human adenovirus type 5 (Ad5), which is replication-incompetent (-E1/-E3) and can’t be integrated into host genome, guaranteeing the security for subsequent operations. Adv packaging by Genemedi shows almost 100% gene delivery in most cell types in the recombinant protein expression system both in vivo and in vitro. Recombinant protein expression of interest is detectable from 24 hours post infection. With the premade adenovirus bought from Genemedi or provided by customers, Genemedi launchs high quality adenovirus amplification service. Adenovirus amplified by Genemedi will be tested to guarantee the quality, the titer of which can be up to 1*10^11 PFU/ml.
|Suitable Types of Infection||In vivo infection in animals|
|Sipping and Storage Guidelines||Shipped by dry ice, stored at -80 ℃, effective for 1 year. Avoid repeatedly freezing and thawing.|
|Titer||> 1*10^11 TU/ml.|
1. Broad range of host. Adv has the ability to infect dividing, quiescent cells, stem cells, and primary cells, allowing genetic materials to be delivered to a highly diverse range of cell types and tissues.
2. High infection efficiency. Almost100% gene delivery in most cell types, completely surpassing other viral vector tools and liposome transfection.
3. High titer. Up to 1011 pfu/ml.
Applications and Figures
Quality control description
Our optimized custom adenoviral vector production and strict quality control systems provide customers a high titer of functional recombinant adenoviral vectors. Viral titers are determined by TCID50 method, which is the most accurate way to measure the titer of adenovirus.
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