It’s the GeneMedi’s summary page for Target/Biomarker Introduction of TAS2R50. The page also collects GeneMedi’s different modalities and formats products for TAS2R50 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the TAS2R50 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). See also TAS2R10 (MIM 604791).[supplied by OMIM, Mar 2008]