human VPS72 Lentivirus plasmid

Cat:pGMLP002477
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLP002477 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLP002477

Gene Name

VPS72

Product Name

human VPS72 Lentivirus plasmid

Accession Number

NM_005997

Gene ID

6944

Species

human

Product Type

Lentivirus plasmid

Insert Length

1095

Gene Alias

CFL1;Swc2;TCFL1;YL-1;YL1

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

Maker

GFP+PURO

Regulation

overexpression