human UGT1A8 Lentivirus plasmid
Cat:pGMLP002393
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP002393
Gene Name
UGT1A8
Product Name
human UGT1A8 Lentivirus plasmid
Accession Number
NM_019076
Gene ID
54576
Species
human
Product Type
Lentivirus plasmid
Insert Length
1593
Gene Alias
UDPGT;UDPGT 1-8;UGT-1H;UGT1-08;UGT1.8;UGT1A8S;UGT1H
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5′ exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids. [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression