human FMO1 Lentivirus plasmid
Cat:pGMLP002377
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days

Description
Catalog ID
pGMLP002377
Gene Name
FMO1
Product Name
human FMO1 Lentivirus plasmid
Accession Number
NM_001282692
Gene ID
2326
Species
human
Product Type
Lentivirus plasmid
Insert Length
1611
Gene Alias
0
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Maker
GFP+PURO
Regulation
overexpression