human NECTIN4 Lentivirus plasmid
Cat:pGMLP002312
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP002312
Gene Name
NECTIN4
Product Name
human NECTIN4 Lentivirus plasmid
Accession Number
NM_030916
Gene ID
81607
Species
human
Product Type
Lentivirus plasmid
Insert Length
1533
Gene Alias
EDSS1;LNIR;nectin-4;PRR4;PVRL4
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
Maker
GFP+PURO
Regulation
overexpression