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human TNFRSF10C Lentivirus plasmid
Cat:pGMLP002252
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP002252
Gene Name
TNFRSF10C
Product Name
human TNFRSF10C Lentivirus plasmid
Accession Number
NM_003841
Gene ID
8794
Species
human
Product Type
Lentivirus plasmid
Insert Length
780
Gene Alias
CD263;DCR1;DCR1-TNFR;LIT;TRAIL-R3;TRAILR3;TRID
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression
