human TNFRSF10C Lentivirus plasmid

Cat:pGMLP002252
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If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLP002252

Gene Name

TNFRSF10C

Product Name

human TNFRSF10C Lentivirus plasmid

Accession Number

NM_003841

Gene ID

8794

Species

human

Product Type

Lentivirus plasmid

Insert Length

780

Gene Alias

CD263;DCR1;DCR1-TNFR;LIT;TRAIL-R3;TRAILR3;TRID

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Maker

GFP+PURO

Regulation

overexpression