human VASP Lentivirus plasmid
Cat:pGMLP002217
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days

Description
Catalog ID
pGMLP002217
Gene Name
VASP
Product Name
human VASP Lentivirus plasmid
Accession Number
NM_003370
Gene ID
7408
Species
human
Product Type
Lentivirus plasmid
Insert Length
1143
Gene Alias
0
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
Maker
GFP+PURO
Regulation
overexpression