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C1S: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It’s the GeneMedi’s summary page for Target/Biomarker Introduction of C1S. The page also collects GeneMedi’s different modalities and formats products for C1S in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the C1S target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
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Target ID |
GM-T76024
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Target Name |
C1S
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Gene ID |
716
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Gene Official Name |
C1S
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Gene Alias |
EDSPD2
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Protein Sub-location |
Secreted Protein/Potential Cytokines
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Category |
Therapeutics Target, INN Index
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Pre-made C1S-specific INN-index biosimilar (antibody&conjugates)-Sutimlimab
Anti-C1S therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
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Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Order |
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Pre-Made Sutimlimab biosimilar, Whole mAb, Anti-C1S Antibody: Anti-EDSPD2 therapeutic antibody |
Sutimlimab |
NA |
C1S |
Whole mAb |
Anti-C1S/ EDSPD2 functional antibody for cell culture, ELISA & in-vivo assay| GMab
Pre-made anti-C1S benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-C1S mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
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Cat No. | Antibody Name | Format | Classified by tag | Order
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|---|---|---|---|---|
Anti-C1S monoclonal antibody |
mab |
FACS/Biofunctional Antibody, Therapeutics Target antibody |
