It’s the GeneMedi’s summary page for Target/Biomarker Introduction of TREML2. The page also collects GeneMedi’s different modalities and formats products for TREML2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the TREML2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008]