TNFRSF10C: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It’s the GeneMedi’s summary page for Target/Biomarker Introduction of TNFRSF10C. The page also collects GeneMedi’s different modalities and formats products for TNFRSF10C in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the TNFRSF10C target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
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Target ID |
GM-MP1854
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Target Name |
TNFRSF10C
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Gene ID |
8794
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Gene Official Name |
TNFRSF10C
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Gene Alias |
CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
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Protein Sub-location |
Transmembrane Protein
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Category |
Cytokine
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Anti-TR10C/ TNFRSF10C/ CD263 antibody for FACS & in-vivo assay| GMab
Pre-made anti-TNFRSF10C benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TNFRSF10C mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cat No. | Antibody Name | Format | Classified by tag | Order
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|---|---|---|---|---|
Anti-TNFRSF10C monoclonal antibody |
mab |
FACS/Biofunctional Antibody, Cytokine antibody |
