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Cat:GMP-h-Proinsulin
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Product Details
Genemedi produces core diagnostic ingredients for test of Diabetes diseases (type 2 diabetes) and related syndrome. GeneMedi offers paired diagnostics grade Human Proinsulin (Proinsulin) antibodies (monoclonal antibody, mab) and antigens for Diabetes diseases (type 2 diabetes) rapid test kit of Human Proinsulin (Proinsulin) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Diabetes diseases (type 2 diabetes ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Proinsulin is the prohormone precursor to
insulin made in the beta cells of the islets of Langerhans, specialized regions
of the pancreas. Increased levels of proinsulin in the circulatory system relative
to mature insulin concentrations can indicate impending insulin resistance and
the development of type 2 diabetes. Postnatal proinsulin is crucial for
metabolic regulation. However, proinsulin in neonates is important for normal
development of the nerves of the eye, development of the heart, and general
survival of embryonic cells. Regulation of the concentration of proinsulin
during embryonic development is crucial, as too much or too little of the
peptide can cause defects and death of the fetus.
Product Description
Cat No. of Pruducts
GMP-h-Proinsulin-Ag01:Recombinant Human Proinsulin Protein
Product Name
Recombinant Human Proinsulin Protein
Target
Human Proinsulin
Alias of Target/Biomarker
IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, PNDM4
Expression platform
E.coli
Isotypes
Recombinant Antigen
Bioactivity validation
Human Proinsulin (Proinsulin) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Proinsulin level test of Diabetes diseases (type 2 diabetes) and related syndrome evaluation
Tag
His
Products description
Recombinant Human Proinsulin Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts
GMP-h-Proinsulin-Ab01,GMP-h-Proinsulin-Ab02:Anti-Human Proinsulin mouse monoclonal antibody (mAb)
Product Name
Anti-Human Proinsulin mouse monoclonal antibody (mAb)
Target
Alias of Target/Biomarker
IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, PNDM4
Expression platform
Hybridoma
Isotypes
Mouse IgG
Bioactivity validation
Human Human Proinsulin (Proinsulin) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Human Proinsulin (Proinsulin) antibodies in Proinsulin level test of Diabetes diseases (type 2 diabetes) and related syndrome evaluation.
Tag
mFc
Products description
Anti-Human Proinsulin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Human Proinsulin (Proinsulin) antibodies.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
