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Cat:GMP-h-ACE2-hFc
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Product Details
Genemedi produces core diagnostic ingredients for test of Lung injury (acute respiratory distress
syndrome) and related syndrome. GeneMedi offers paired diagnostics grade Human Angiotensin Converting Enzyme 2 (ACE2/hFc) antibodies (monoclonal antibody, mab) and antigens for Lung injury (acute respiratory distress
syndrome) rapid test kit of Human Angiotensin Converting Enzyme 2 (ACE2/hFc) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Lung injury (acute respiratory distress
syndrome ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Angiotensin-converting enzyme 2 (ACE2) is an
enzyme that can be found either attached to the membrane of cells (mACE2) in
the intestines, kidney, testis, gallbladder, and heart or in a soluble form
(sACE2). Both membranes bound and soluble ACE2 are integral parts of the renin–angiotensin–aldosterone
system (RAAS) that exists to maintain the body’s blood pressure. As a
transmembrane protein, mACE2 serves as the main entry point into cells for some
coronaviruses, including HCoV-NL63, SARS-CoV and SARS-CoV-2. The binding of the
SARS-CoV-2 virus through mACE2 receptors present in heart tissue may be
responsible for direct viral injury leading to myocarditis. human ACE2 (rhACE2)
is surmised to be a novel therapy for acute lung injury, and appeared to
improve pulmonary blood flow and oxygen saturation in piglets with a
lipopolysaccharide-induced acute respiratory distress syndrome
Product Description
Cat No. of Pruducts
GMP-h-ACE2-hFc-Ag01:Recombinant Human ACE2/hFc Protein
Product Name
Recombinant Human ACE2/hFc Protein
Target
Human Angiotensin Converting Enzyme 2
Alias of Target/Biomarker
ACEH
Expression platform
E.coli
Isotypes
Recombinant Antigen
Bioactivity validation
Human Angiotensin Converting Enzyme 2 (ACE2/hFc) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of Lung injury (acute respiratory distress
syndrome) and related syndrome evaluation
Tag
His
Products description
Recombinant Human ACE2/hFc Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts
GMP-h-ACE2-hFc-Ab01,GMP-h-ACE2-hFc-Ab02:Anti-Human ACE2/hFc mouse monoclonal antibody (mAb)
Product Name
Anti-Human ACE2/hFc mouse monoclonal antibody (mAb)
Target
Alias of Target/Biomarker
ACEH
Expression platform
Hybridoma
Isotypes
Mouse IgG
Bioactivity validation
Human Human Angiotensin Converting Enzyme 2 (ACE2/hFc) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Human Angiotensin Converting Enzyme 2 (ACE2/hFc) antibodies in ACE2/hFc level test of Lung injury (acute respiratory distress
syndrome) and related syndrome evaluation.
Tag
mFc
Products description
Anti-Human ACE2/hFc mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Human Angiotensin Converting Enzyme 2 (ACE2/hFc) antibodies.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
