Cat:GMP-h-a-defensin-5
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Product Details

Genemedi produces core diagnostic ingredients for test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome. GeneMedi offers paired diagnostics grade alpha defensin 5 (α-defensin 5) antibodies (monoclonal antibody, mab) and antigens for Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) rapid test kit of alpha defensin 5 (α-defensin 5) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI) ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Alpha defensins are a family of mammalian defensin peptides of the alpha subfamily. Prosthetic joint infection (PJI) management is not standardized worldwide. Diagnosis of PJI remains challenging because the clinical signs and symptoms and elevation of systemic biomarkers (C-reactive protein, erythrocyte sedimentation rate) may be unclear. Synovial biomarkers have shown encouraging results and they should be used as diagnostic adjuncts to synovial white cell count and culture bacteriology. Synovial leukocyte esterase (LE) and synovial C-reactive protein (CRP) have been evaluated as good screening measures; however, the most promising synovial fluid biomarker in terms of sensitivity and specificity for PJI seems to be alpha defensin (AD). alpha defensin lateral flow test could have its place in ruling in a suspected PJI intraoperatively because of its high specificity and rapid results.

Product Description

Cat No. of Pruducts

GMP-h-a-defensin-5-Ag01:Recombinant Human ¦Á-defensin 5 Protein

Product Name

Recombinant Human α-defensin 5 Protein

Target

alpha defensin 5

Alias of Target/Biomarker

DEFA5, DEF5, HD-5

Expression platform

synthesized

Isotypes

Peptide Antigen

Bioactivity validation

alpha defensin 5 (α-defensin 5) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation

Tag

NA

Products description

Recombinant Human α-defensin 5 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts

GMP-h-a-defensin-5-Ab01,GMP-h-a-defensin-5-Ab02:Anti-Human ¦Á-defensin 5 mouse monoclonal antibody (mAb)

Product Name

Anti-Human α-defensin 5 mouse monoclonal antibody (mAb)

Target

alpha defensin 5 (α-defensin 5)

Alias of Target/Biomarker

DEFA5, DEF5, HD-5

Expression platform

Hybridoma

Isotypes

Mouse IgG

Bioactivity validation

Human alpha defensin 5 (α-defensin 5) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other alpha defensin 5 (α-defensin 5) antibodies in α-defensin 5 level test of Inflammation/autoimmune/inflammatory disease (Prosthetic joint infection (PJI)) and related syndrome evaluation.

Tag

mFc

Products description

Anti-Human α-defensin 5 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other alpha defensin 5 (α-defensin 5) antibodies.

Reconized/Reactive Species

Human

Purity

Purity: ≥95% (SDS-PAGE)

Application

ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT

Formulation

Supplied as a 0.2 μM filtered solution of PBS,PH7.4.

Storage

Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1

Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.