Anti-TNFSF12-TNFSF13/ TWE-PRIL functional antibody for cell culture, ELISA & in-vivo assay| GMab

Cat:GM-Tg-hg-SE0519-Ab
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$3,090.00

SKU GM-Tg-hg-SE0519-Ab Category

Description

Pre-made anti-TNFSF12-TNFSF13 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TNFSF12-TNFSF13 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: TNFSF12-TNFSF13, gene name: TNFSF12-TNFSF13, also named as TWE-PRIL. This gene encodes a member of the tumor necrosis factor superfamily. It encodes a hybrid protein composed of the cytoplasmic and transmembrane domains of family member 12 fused to the C-terminal domain of family member 13. The hybrid protein is membrane anchored and presents the receptor-binding domain of family member 13 at the cell surface. It stimulates cycling in T- and B-lymphoma cell lines. [provided by RefSeq, Jul 2008].

Antigen Information

Catalog No.

GM-Tg-hg-SE0519-Ab-1,GM-Tg-hg-SE0519-Ab-2

Product Name

Anti-TNFSF12-TNFSF13 monoclonal antibody

Format

mab

Target Name

TNFSF12-TNFSF13

Gene ID

TNFSF12-TNFSF13

Gene Name

TNFSF12-TNFSF13

Gene Alias

TWE-PRIL

Protein Sub-location

Secreted Protein/Potential Cytokines

Category of antibody

FACS/Biofunctional Antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-TNFSF12-TNFSF13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.