Anti-TNF18/ TNFSF18/ AITRL antibody for FACS & in-vivo assay| GMab

Cat:GM-Tg-hg-MP1858-Ab
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$3,090.00

SKU GM-Tg-hg-MP1858-Ab Category

Description

Pre-made anti-TNFSF18 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TNFSF18 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: TNFSF18, gene name: TNFSF18, also named as AITRL, GITRL, TL6, TNLG2A, hGITRL. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008].

Antigen Information

Catalog No.

GM-Tg-hg-MP1858-Ab-1,GM-Tg-hg-MP1858-Ab-2

Product Name

Anti-TNFSF18 monoclonal antibody

Format

mab

Target Name

TNFSF18

Gene ID

TNFSF18

Gene Name

TNFSF18

Gene Alias

AITRL, GITRL, TL6, TNLG2A, hGITRL

Protein Sub-location

Transmembrane Protein

Category of antibody

FACS/Biofunctional Antibody, Cytokine antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-TNFSF18 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.