Calcium homeostasis depends on the reabsorption of bone by osteoclasts and the development of bone by osteoblasts. Imbalance between these two metabolisms leads to osteoporosis. Osteoporosis is a health condition characterized by low bone density, making them fragile and more risk of bone fracture. Osteoporosis develops gradually over several years and is often diagnosed by the […]
Category Archives: IVD
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and […]
High blood pressure (hypertension) is a common disorder. it may eventually cause health problems, such as heart disease. Subgroups of the patients have been identified on the basis of their responses to hormonal and biologic stimuli. These subgroups include low-renin hypertensives and nonmodulators. Aldosterone, the principal human mineralocorticoid, which control blood pressure by holding onto […]
Valproate is a commonly used antiepileptic drug for the treatment of epilepsy and seizures. It is safe for use in both adults and children more than three years of age. Valproate toxicity can occur both accidentally and intentionally. Acute valproate overdose usually presents with CNS depression/encephalopathy, electrolyte abnormalities such as hypernatremia, elevated transaminase levels, hyperammonemia, and […]
Chronic atrophic gastritis (CAG) with intestinal metaplasia is recognized to be a precancerous lesion that can evolve toward low- and high-grade intraepithelial lesions and gastric cancer. CAG is characterized by loss of gastric glands and can be evaluated endoscopically, histologically and serologically. Therefore, its early detection is a priority in preventing gastric cancer. Hence, biomarkers […]
Acetaminophen is known as paracetamol in many countries outside the US. It is one of the most frequently used oral analgesics and antipyretics. It has an outstanding safety profile when administered in an appropriate dose, but hepatotoxicity can occur after overdose or when misused in at-risk populations. GENEMEDI developed the antigens and antibodies for the diagnosis […]
Autoimmune diseases occur when the immune system attacks the normal tissue within joints, vasculature, and other organ systems, causing inflammation, pain, diminished mobility, fatigue, and other non-specific symptoms.1 The strong overlap of signs and symptoms among the autoimmune diseases can lead to delays in diagnosis and appropriate treatment. However, immunodiagnostics has been developed to detect […]
Full List Download Gastric disorders are the most common disease leads to the death. Most death of gastric disease is mostly due the diagnosis at late-stage. The diagnosis of Gastric disease at early-stage is delayed due to the lack symptoms and effective diagnostic technique. The traditional technology, including endoscopic examination and gastroscopic biopsy are invasive […]
Full List Download The kidneys are important to filter wastes and excess fluids from the blood and excreted in urine. Chronic kidney disease steadily loss the kidney function and fail to filter the waste in the body. The chronic kidney disease (CKD) includes advanced stage of renal parenchyma damage and the loss of functional nephrons. […]
Thyroid gland produces the hormones that keep body functioning normally. When concentration of these hormone increases or decrease, it’s called a thyroid disease. There are several types of thyroid disease, which includes hyperthyroidism, hypothyroidism, thyroiditis and Hashimoto’s thyroiditis. The most commonly measured thyroid hormones are thyroid stimulating hormone (TSH), total thyroxine (T4), free T4, total triiodothyronine (T3), […]
