Products list of Spike trimer (P2-mutant, S1/S2 cleavage site (furin cleavage sequence)-mutant, trimerization modified) SARS-CoV-2 P2-mutated Spike protein trimer variant (P2-mutant, S1/S2 cleavage site（furin cleavage sequence)-mutant, trimerization modified) The world is in midst of the COVID-19 pandemic caused by SARS-CoV-2 (2019nCoV) infection. The Spike protein (S-protein) of SARS-CoV-2 (2019nCoV) mediates receptor (ACE2) binding and cell […]
Category Archives: diagnostic article
Variant of Concern 202012/01Technical briefing 2 Nomenclature of variants in the UK SARS-CoV-2 variants if considered to have concerning epidemiological, immunological or pathogenic properties are raised for formal investigation. At this point they are designated Variant Under Investigation (VUI) with a year, month, and number. Following risk assessment with the relevant expert committee, they may […]
PDF Download The ongoing worldwide severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic has a tremendous influence on public health. There is an urgent need for developing accurate detection technologies for COVID-19 pandemic. Several diagnostic strategies are available to identify or rule out current infection, identify people in need of care escalation, or to test […]
Summary of request This analysis uses data from the COVID-19 Infection Survey up to 21 December 2020. The analysis looks to establish whether there are patterns in the associations of different types of positives within household pairs. This analysis was undertaken by Thomas House, University of Manchester Date of publication: 29th December 2020 Contents: Data: […]
NOVEL VARIANT INCIDENT MANAGEMENT TEAM PUBLIC HEALTH ENGLAND WITH IMPERIAL COLLEGE, THE UNIVERSITY OF EDINBURGH, THE UNIVERSITY OF BIRMINGHAM AND THE WELLCOME SANGER INSTITUTE Update on the submission of 11/12/20 New information:1. Investigation of S gene target failure cases and new epidemiology data2. Modelling on transmissibility3. Proposed risk assessment NERVTAG is asked to▪ Note the […]
New and Emerging Respiratory Virus Threats Advisory Group Note of meeting Date & Location of meeting: 11:00 –13.00 18December2020 -Via telecon only In attendance: Chair: Peter Horby (PH) NERVTAG Members: Peter Openshaw (PO), Andrew Hayward (AH),Wei Shen Lim (WSL),Julian Hiscox (JHi),John Edmunds (JE), Neil Ferguson (NF), Robert Dingwall (RD),Muge Cevik (MCe), Wendy Barclay (WB), Jim McMenamin […]
New and Emerging Respiratory Virus Threats Advisory Group Note of meeting Date & Location: 12:00 –13.30 21 December 2020 -Via telecon only In attendance: Chair: Peter Horby (PH) NERVTAG Members: Andrew Hayward (AH), Julian Hiscox (JHi), John Edmunds (JE), Neil Ferguson (NF), Wendy Barclay (WB),Wei Shen Lim (WSL), Cariad Evans (CE) SPI-M: Angela McLean (AM), Graham […]
New strain of COVID-19 reported to World Health Organization. Chief Medical Officer for England, Professor Chris Whitty, said: “As announced on Monday, the UK has identified a new variant of COVID-19 through Public Health England’s genomic surveillance.” “As a result of the rapid spread of the new variant, preliminary modelling data and rapidly rising […]
Two cases of a new SARS-CoV-2 variant, which originated in South Africa, have been identified in the UK. The 2 cases were identified in the UK on 22 December 2020 and both have been in contact with someone who has travelled from South Africa. Public Health England’s Health Protection Teams have followed up with both […]
Public Health England (PHE) has confirmed that lateral flow devices (LFDs) used in mass testing can detect the new COVID-19 variant. Scientists at PHE’s Porton Down laboratory have carried out a rapid evaluation using clinical and laboratory grown samples containing the VUI 202012/01 variant to test whether it can be detected by lateral flow devices (LFDs) currently in […]
