Pre-Made Citatuzumab Bogatox biosimilar, Fusion Protein, Citatuzumab-Anti-EPCAM Antibody: Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 therapeutic antibody fused with Bougainvillea spectabilis Willd bouganin for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-781

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SKU GMP-Bios-INN-781 Category Tag

Product Details

Pre-Made Citatuzumab Bogatox biosimilar, Fusion Protein, Citatuzumab-Anti-EPCAM Antibody: Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 therapeutic antibody fused with Bougainvillea spectabilis Willd bouganin is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Citatuzumab bogatox (VB6-845) is a monoclonal antibody Fab fragment fused with bouganin, a ribosome inactivating protein from the plant Bougainvillea spectabilis.[1] It has undergone preclinical development for the treatment of ovarian cancer and other solid tumors.[2]

Products Name (INN Index)

Pre-Made Citatuzumab Bogatox biosimilar, Fusion Protein, Citatuzumab-Anti-EPCAM Antibody: Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 therap

INN Name

citatuzumab bogatox

Target

EPCAM

Format

Fusion Protein

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

Fab – G1 – kappa

VD LC

Fab – G1 – kappa

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

Viventia Biotechnologies?Inc. (Mississauga ON Canada)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

EPCAM

Package

, ,

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