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Pre-made Tecaginlimab benchmark antibody ( Whole mAb, anti-CD40;TNFRSF9/CD137 therapeutic antibody, Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 Antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-ab-701
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Product Details
Pre-Made Tecaginlimab biosimilar, Whole mAb, Anti-CD40;TNFRSF9/CD137 Antibody: Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Products Name (INN Index) | Pre-Made Tecaginlimab biosimilar, Whole mAb, Anti-CD40;TNFRSF9/CD137 Antibody: Anti-p50/Bp50/CDW40/TNFRSF5;ILA/4-1BB/CDw137 therapeutic antibody |
|---|---|
| INN Name | Tecaginlimab |
| Target | CD40,TNFRSF9 |
| Format | Bispecific Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | G1;G1 |
| VD LC | Kappa,Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I/II |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2021 |
| Year Recommended | NA |
| Companies | Genmab |
| Conditions Approved | NA |
| Conditions Active | Solid tumours |
| Conditions Discontinued | NA |
| Development Tech | DuoBody |
| Previous Name | NA |
| Gm Offical Target Name | CD40,TNFRSF9 |
| Package |
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