Pre-made Sofituzumab benchmark antibody ( Whole mAb ADC, anti-MUC16 therapeutic antibody, Anti-CA125 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-526

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SKU GMP-Bios-ab-526 Category Tag

Product Details

Pre-Made Sofituzumab biosimilar, Whole mAb ADC, Anti-MUC16 Antibody: Anti-CA125 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Sofituzumab vedotin (INN; development code DMUC5754A) is a monoclonal antibody designed for the treatment of ovarian cancer. This drug was developed by Genentech/Roche.

Products Name (INN Index)

Pre-Made Sofituzumab biosimilar, Whole mAb ADC, Anti-MUC16 Antibody: Anti-CA125 therapeutic antibody

INN Name

Sofituzumab

Target

MUC16

Format

Whole mAb ADC

Derivation

NA

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-I

Est. Status

Discontinued

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2013

Companies

Genentech

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

Fallopian tube cancer,Ovarian cancer,Pancreatic cancer,Peritoneal cancer

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

MUC16

Package

, ,

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