Pre-made Sacituzumab benchmark antibody ( Whole mAb ADC, anti-TACSTD2 therapeutic antibody, Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-503

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SKU GMP-Bios-ab-503 Category Tag

Product Details

Pre-Made Sacituzumab biosimilar, Whole mAb ADC, Anti-TACSTD2 Antibody: Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Sacituzumab govitecan-hziy injection is used to treat triple-negative breast cancer that has spread (metastatic) or cannot be removed by surgery (unresectable locally advanced). It is given to patients who have received 2 or more cancer treatments, including at least 1 treatment for metastatic disease.

Products Name (INN Index)

Pre-Made Sacituzumab biosimilar, Whole mAb ADC, Anti-TACSTD2 Antibody: Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 therapeutic antibody

INN Name

Sacituzumab

Target

TACSTD2

Format

Whole mAb ADC

Derivation

Humanized

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2016

Companies

IBC Pharmaceuticals,Immunomedics,University of Wisconsin Comprehensive Cancer Center,Yale University

Conditions Approved

Breast cancer

Conditions Active

Prostate cancer,Solid tumours,Urogenital cancer,Endometrial cancer,Glioblastoma

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

TACSTD2

Package

, ,

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