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Pre-made Oxelumab benchmark antibody ( Whole mAb, anti-TNFSF4/OX40 therapeutic antibody, Anti-CD134L/CD252/GP34/OX-40L/OX4OL/TNLG2B/TXGP1 Antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-ab-417
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Product Details
Pre-Made Oxelumab biosimilar, Whole mAb, Anti-TNFSF4/OX40 Antibody: Anti-CD134L/CD252/GP34/OX-40L/OX4OL/TNLG2B/TXGP1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Oxelumab is a human monoclonal antibody designed for the treatment of asthma.
| Products Name (INN Index) | Pre-Made Oxelumab biosimilar, Whole mAb, Anti-TNFSF4/OX40 Antibody: Anti-CD134L/CD252/GP34/OX-40L/OX4OL/TNLG2B/TXGP1 therapeutic antibody |
|---|---|
| INN Name | Oxelumab |
| Target | TNFSF4 |
| Format | Whole mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2010 |
| Year Recommended | 2011 |
| Companies | Genentech,Genmab,Roche |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | Allergic asthma,Allergic rhinitis |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | TNFSF4 |
| Package |
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