Pre-made Naratuximab benchmark antibody ( Whole mAb ADC, anti-CD37 therapeutic antibody, Anti-GP52-40/TSPAN26 Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-364

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SKU GMP-Bios-ab-364 Category Tag

Product Details

Pre-Made Naratuximab biosimilar, Whole mAb ADC, Anti-CD37 Antibody: Anti-GP52-40/TSPAN26 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Naratuximab emtansine | IMGN529 (K7153A) | Debio 1562 | Drug Description. … The investigational drug is in clinical trials for the potential treatment of non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, B-Cell Lymphomas. CD37, a transmembrane glycoprotein, is overexpressed in B-cell malignancies.

Products Name (INN Index)

Pre-Made Naratuximab biosimilar, Whole mAb ADC, Anti-CD37 Antibody: Anti-GP52-40/TSPAN26 therapeutic antibody

INN Name

Naratuximab

Target

CD37

Format

Whole mAb ADC

Derivation

Chimeric (Mouse/Human)

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Phase-II

Est. Status

Active

100% SI Structure

None

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2015

Companies

ImmunoGen,Chronic lymphocytic leukaemia

Conditions Approved

NA

Conditions Active

Diffuse large B cell lymphoma,Non-Hodgkin's lymphoma

Conditions Discontinued

Chronic lymphocytic leukaemia

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

CD37

Package

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