Pre-made Bezlotoxumab benchmark antibody ( Whole mAb, anti-Toxin A therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-067

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SKU GMP-Bios-ab-067 Category Tag

Product Details

Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infections.

Products Name (INN Index)

Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody

INN Name

Bezlotoxumab

Target

Toxin A

Format

Whole mAb

Derivation

Human

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

NFD

100% SI Structure

4np4:HL:IM

99% SI Structure

None

95-98% SI Structure

None

Year Proposed

2012

Companies

Medarex,University of Massachusetts Medical School,Merck & Co,Merck Sharp & Dohme

Conditions Approved

Clostridium difficile

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

Medarex HuMAb Mouse

Previous Name

NA

Gm Offical Target Name

Toxin A

Package

, ,

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