Pre-made Adalimumab benchmark antibody ( Whole mAb, anti-TNFA/TNF therapeutic antibody, Anti-DIF/TNFSF2/TNLG1F Antibody) for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-ab-009

* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry

SKU GMP-Bios-ab-009 Category Tag

Product Details

Pre-Made Adalimumab biosimilar, Whole mAb, Anti-TNFA/TNF Antibody: Anti-DIF/TNFSF2/TNLG1F therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Adalimumab, sold under the brand name Humira, among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, psoriasis, hidradenitis suppurativa, uveitis, and juvenile idiopathic arthritis. Use is generally only recommended in people who have not responded to other treatments. It is administered by injection under the skin.

Products Name (INN Index)

Pre-Made Adalimumab biosimilar, Whole mAb, Anti-TNFA/TNF Antibody: Anti-DIF/TNFSF2/TNLG1F therapeutic antibody

INN Name

Adalimumab

Target

TNF

Format

Whole mAb

Derivation

Human

Species Reactivity

Human

CH1 Isotype

IgG1

VD LC

Kappa

Highest_Clin_Trial (Jan '20)

Approved

Est. Status

Active

100% SI Structure

6cr1:HL/4nyl:AB:CD:EF:HL

99% SI Structure

3wd5:HL

95-98% SI Structure

None

Year Proposed

1999

Companies

Abbvie,MedImmune,180 Life Sciences

Conditions Approved

Ankylosing spondylitis,Behcet's syndrome,Crohn's disease,Hidradenitis suppurativa,Juvenile rheumatoid arthritis,Plaque psoriasis,Psoriatic arthritis,Pustular psoriasis,Rheumatoid arthritis,Spondylart

Conditions Active

Dupuytren's contracture,Cognition disorders,Frozen shoulder,Non-alcoholic steatohepatitis

Conditions Discontinued

Interstitial cystitis

Development Tech

CAT Phage Display

Previous Name

NA

Gm Offical Target Name

TNFA/TNF

Package

, ,

Genemeidi Omicron Variant Products
test
Previous slide
Next slide