AAV1 Rep-Cap plasmid (serotype 1- specific AAV RC1 plasmids)

GeneMedi’s AAV1 Rep-Cap plasmid (serotype 1-specific AAV RC plasmid), also named AAV1-RC plasmid, or AAV-RC1 plasmid, is part of AAV1 packaging system. AAV1 Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV1 capsid protein.

You can produce AAV1 paticle in 293T cell line in high titer using GeneMedi’s AAV1 Rep-Cap plasmid with GeneMedi’s AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

The tissue tropism of AAV1 vector has been validated in neuron(CNS), heart, muscle, retina and Pancreas, with potential applications in tissue-specific gene therapy.