Cat:pGMAD000005
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMAD000005 Categories , , ,

Availability:3-7 business days

Description

Catalog ID

pGMAD000005

Gene Name

PKLR

Product Name

Accession Number

NM_000298.5

Gene ID

5313

Species

human

Product Type

Adenovirus plasmid

Insert Length

1725

Gene Alias

PK1;PKL;PKR;PKRL;RPK

Fluorescent Label

NULL

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Maker

NULL

Regulation

overexpression