human IL4I1 Lentivirus plasmid

Cat:pGMLP002445
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLP002445

Gene Name

IL4I1

Product Name

human IL4I1 Lentivirus plasmid

Accession Number

NM_152899

Gene ID

259307

Species

human

Product Type

Lentivirus plasmid

Insert Length

1704

Gene Alias

FIG1;LAAO;LAO

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

This gene encodes a secreted L-amino acid oxidase protein which primarily catabolizes L-phenylalanine and, to a lesser extent, L-arginine. The expression of this gene is induced by the cytokine interleukin 4 in B cells. This gene is also expressed in macrophages and dendritic cells. This protein may play a role immune system escape as it is expressed in tumor-associated macrophages and suppresses T-cell responses. This protein also contains domains thought to be involved in the binding of flavin adenine dinucleotide (FAD) cofactor. Multiple transcript variants encoding different isoforms have been found for this gene. Some transcripts of this gene share a promoter and exons of the 5′ UTR with the overlapping NUP62 gene. [provided by RefSeq, Jul 2020]

Maker

GFP+PURO

Regulation

overexpression