human KPNA6 Lentivirus plasmid

Cat:pGMLP002408
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
SKU pGMLP002408 Categories , , , Tag

Availability:3-7 business days

Description

Catalog ID

pGMLP002408

Gene Name

KPNA6

Product Name

human KPNA6 Lentivirus plasmid

Accession Number

NM_012316

Gene ID

23633

Species

human

Product Type

Lentivirus plasmid

Insert Length

1611

Gene Alias

IPOA7;KPNA7

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]

Maker

GFP+PURO

Regulation

overexpression