human PCGF2 Lentivirus plasmid

Cat:pGMLP002296
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
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Availability:3-7 business days

Description

Catalog ID

pGMLP002296

Gene Name

PCGF2

Product Name

human PCGF2 Lentivirus plasmid

Accession Number

NM_007144

Gene ID

7703

Species

human

Product Type

Lentivirus plasmid

Insert Length

1035

Gene Alias

MEL-18;RNF110;ZNF144

Fluorescent Label

GFP+PURO

Fusion Tag

3×flag

Promoter

CMV

Resistance

Amplicin

gene description

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]

Maker

GFP+PURO

Regulation

overexpression