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human LIN28B Lentivirus plasmid
Cat:pGMLP002258
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days
Description
Catalog ID
pGMLP002258
Gene Name
LIN28B
Product Name
human LIN28B Lentivirus plasmid
Accession Number
NM_001004317.3
Gene ID
389421
Species
human
Product Type
Lentivirus plasmid
Insert Length
753
Gene Alias
CSDD2
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3′ UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Maker
GFP+PURO
Regulation
overexpression
