human GFRA2 Lentivirus plasmid
Cat:pGMLP002235
If you purchase ORF/cDNA clone-Lentivirus plasmid, ORF vector will be delivered with P-ALV-B11 backbone together.
Availability:3-7 business days

Description
Catalog ID
pGMLP002235
Gene Name
GFRA2
Product Name
human GFRA2 Lentivirus plasmid
Accession Number
NM_001495
Gene ID
2675
Species
human
Product Type
Lentivirus plasmid
Insert Length
1395
Gene Alias
GDNFRB;NRTNR-ALPHA;NTNRA;RETL2;TRNR2
Fluorescent Label
GFP+PURO
Fusion Tag
3×flag
Promoter
CMV
Resistance
Amplicin
gene description
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Maker
GFP+PURO
Regulation
overexpression