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IFNG: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It’s the GeneMedi’s summary page for Target/Biomarker Introduction of IFNG. The page also collects GeneMedi’s different modalities and formats products for IFNG in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the IFNG target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
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Target ID |
GM-T77664
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Target Name |
IFNG
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Gene ID |
3458
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Gene Official Name |
IFNG
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Gene Alias |
IFG, IFI
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Protein Sub-location |
Secreted Protein/Potential Cytokines
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Category |
Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target, INN Index, Cytokine
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Pre-made IFNG-specific INN-index biosimilar (antibody&conjugates)-Emapalumab, Fontolizumab
Anti-IFNG therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
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Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Order |
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Pre-Made Emapalumab biosimilar, Whole mAb, Anti-IFNG Antibody: Anti-IFG/IFI/IMD69 therapeutic antibody |
Emapalumab |
NA |
IFNG |
Whole mAb |
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Pre-Made Fontolizumab biosimilar, Whole mAb, Anti-IFNG Antibody: Anti-IFG/IFI/IMD69 therapeutic antibody |
Fontolizumab |
NA |
IFNG |
Whole mAb |
Anti-IFNG/ IFG/ IFI functional antibody for cell culture, ELISA & in-vivo assay| GMab
Pre-made anti-IFNG benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IFNG mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
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Cat No. | Antibody Name | Format | Classified by tag | Order
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|---|---|---|---|---|
Anti-IFNG monoclonal antibody |
mab |
FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody |
