IL6: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It’s the GeneMedi’s summary page for Target/Biomarker Introduction of IL6. The page also collects GeneMedi’s different modalities and formats products for IL6 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi’s target-insight database-GM ITD database, the IL6 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]

Target ID

GM-T32578

Target Name

IL6

Gene ID

3569

Gene Official Name

IL6

Gene Alias

BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6

Protein Sub-location

Secreted Protein/Potential Cytokines

Category

Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target, INN Index, Cytokine

Pre-made IL6-specific INN-index biosimilar (antibody&conjugates)-olamkicept, Ziltivekimab, Siltuximab, elsilimomab, Sirukumab, Clazakizumab, Olokizumab

Anti-IL6 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Filters Sort results
Reset Apply
Cat No.
Products Name (INN Index)
INN Name
Previous Name
Target
Format
Order
Pre-Made Clazakizumab biosimilar, Whole mAb, Anti-IL6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
Clazakizumab
NA
IL6
Whole mAb
Pre-Made Olokizumab biosimilar, Whole mAb, Anti-IL6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
Olokizumab
NA
IL6
Whole mAb
Pre-Made Siltuximab biosimilar, Whole mAb, Anti-IL6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
Siltuximab
NA
IL6
Whole mAb
Pre-Made Sirukumab biosimilar, Whole mAb, Anti-IL6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
Sirukumab
NA
IL6
Whole mAb
Pre-Made Ziltivekimab biosimilar, Whole mAb, Anti-IL6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
Ziltivekimab
NA
IL6
Whole mAb
Pre-Made Elsilimomab Biosimilar, Whole Mab, Anti-Il6 Antibody: Anti-BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6 therapeutic antibody
elsilimomab
NA
IL6
Whole mAb
Pre-Made Olamkicept Biosimilar, Fusion Protein targeting IL6 fused with human IGHG1 Fc (Fragment constant): Recombinant therapeutic protein targeting BSF-2/BSF2/CDF/HGF/HSF/IFN-beta-2/IFNB2/IL-6
olamkicept
NA
IL6
Fusion Protein

Anti-IL6/ BSF-2/ BSF2 functional antibody for cell culture, ELISA & in-vivo assay| GMab

Pre-made anti-IL6 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IL6 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Filters Sort results
Reset Apply
Cat No.
Antibody Name
Format
Classified by tag
Order
Anti-IL6 monoclonal antibody
mab
FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody