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Cat:GMP-h-GDF-15
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Product Details
Genemedi produces core diagnostic ingredients for test of Cardiovascular disease (pressure overload,
myocardial infarction, heart failure, and atherosclerosis) and related syndrome. GeneMedi offers paired diagnostics grade Growth differentiation factor-15 (GDF-15) antibodies (monoclonal antibody, mab) and antigens for Cardiovascular disease (pressure overload,
myocardial infarction, heart failure, and atherosclerosis) rapid test kit of Growth differentiation factor-15 (GDF-15) testing in standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Cardiovascular disease (pressure overload,
myocardial infarction, heart failure, and atherosclerosis ) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody. The antigens can be used as positive control.Growth and differentiation
factor 15 (GDF-15), previously known as macrophage inhibitory cytokine 1
(MIC-1), is a divergent transforming growth factor β (TGF-β) family member
historically associated with cancer cachexia, cardiovascular disease, and a
host of other diseases with inflammatory etiologies. GDF-15 is expressed in
most tissues only at very low levels, the only human organ that expresses high
levels of GDF-15 in healthy conditions is the placenta. However, GDF-15 could
be markedly increased in the case of cardiovascular injury, such as pressure
overload, myocardial infarction, heart failure, and atherosclerosis.
Product Description
Cat No. of Pruducts
GMP-h-GDF-15-Ag01:Recombinant Human GDF-15 Protein
Product Name
Recombinant Human GDF-15 Protein
Target
Growth differentiation factor-15
Alias of Target/Biomarker
GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Expression platform
E.coli
Isotypes
Recombinant Antigen
Bioactivity validation
Growth differentiation factor-15 (GDF-15) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of Cardiovascular disease (pressure overload,
myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation
Tag
His
Products description
Recombinant Human GDF-15 Protein was expressed in E.coli -based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
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Cat No. of Pruducts
GMP-h-GDF-15-Ab01,GMP-h-GDF-15-Ab02:Anti-Human GDF-15 mouse monoclonal antibody (mAb)
Product Name
Anti-Human GDF-15 mouse monoclonal antibody (mAb)
Target
Alias of Target/Biomarker
GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Expression platform
Hybridoma
Isotypes
Mouse IgG
Bioactivity validation
Human Growth differentiation factor-15 (GDF-15) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Growth differentiation factor-15 (GDF-15) antibodies in GDF-15 level test of Cardiovascular disease (pressure overload,
myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation.
Tag
mFc
Products description
Anti-Human GDF-15 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Growth differentiation factor-15 (GDF-15) antibodies.
Reconized/Reactive Species
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation
Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage
Store at? -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.
Diagnostic antibodies and antigens for cancer detection - TG, CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, FER, CYFRA21-1, HER2, HSP90α, S100B, CEA, AFP, sFlt-1, PSA, hEGF, TFF2, TFF3, CA199, CA50, TK1
Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several cancers such as anal, breast, ovaries, testicles, colon, endometrial, peritoneal, fallopian tube, gallbladder, gastric, liver, lung, neuroendocrine, pancreatic, prostate, renal, cervix, stomach and thyroid cancer, bronchopulmonary dysplasia, hepatitis, hematological malignancies, hemochromatosis, hypercalcemia, osteoporosis, Parget’s diseases and so on have been identified using specific marker. Detecting the quantity of marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
