Pre-made anti-PRDX5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.

Cat:GM-Tg-hg-T77009-Ab
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$3,090.00

SKU GM-Tg-hg-T77009-Ab Category

Description

Pre-made anti-PRDX5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PRDX5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: PRDX5, gene name: PRDX5, also named as ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017].

Antigen Information

Catalog No.

GM-Tg-hg-T77009-Ab-1,GM-Tg-hg-T77009-Ab-2

Product Name

Anti-PRDX5 monoclonal antibody

Format

mab

Target Name

PRDX5

Gene ID

PRDX5

Gene Name

PRDX5

Gene Alias

ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V

Protein Sub-location

Introcelluar Protein

Category of antibody

Therapeutics Target antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.

Tag

Fc

Products description

Pre-made anti-PRDX5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.