Anti-IL1R1/ CD121A/ D2S1473 antibody for FACS & in-vivo assay| GMab
Cat:GM-Tg-hg-T72515-Ab
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$3,090.00
SKU
GM-Tg-hg-T72515-Ab
Category Target Antibody
Description
Pre-made anti-IL1R1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IL1R1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: IL1R1, gene name: IL1R1, also named as CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80. This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013].
Antigen Information
Catalog No.
GM-Tg-hg-T72515-Ab-1,GM-Tg-hg-T72515-Ab-2
Product Name
Anti-IL1R1 monoclonal antibody
Format
mab
Target Name
IL1R1
Gene ID
IL1R1
Gene Name
IL1R1
Gene Alias
CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Protein Sub-location
Transmembrane Protein
Category of antibody
FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-IL1R1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.