Anti-IL1R1/ CD121A/ D2S1473 antibody for FACS & in-vivo assay| GMab

Cat:GM-Tg-hg-T72515-Ab
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$3,090.00

SKU GM-Tg-hg-T72515-Ab Category

Description

Pre-made anti-IL1R1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IL1R1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: IL1R1, gene name: IL1R1, also named as CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80. This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013].

Antigen Information

Catalog No.

GM-Tg-hg-T72515-Ab-1,GM-Tg-hg-T72515-Ab-2

Product Name

Anti-IL1R1 monoclonal antibody

Format

mab

Target Name

IL1R1

Gene ID

IL1R1

Gene Name

IL1R1

Gene Alias

CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80

Protein Sub-location

Transmembrane Protein

Category of antibody

FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-IL1R1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.