Anti-MMP21/ MMP-21/ HTX7 functional antibody for cell culture, ELISA & in-vivo assay| GMab
Cat:GM-Tg-hg-T68443-Ab
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$3,090.00
SKU
GM-Tg-hg-T68443-Ab
Category Target Antibody
Description
Pre-made anti-MMP-21 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-MMP-21 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: MMP-21, gene name: MMP21, also named as HTX7, MMP-21. This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013].
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Antigen Information
Catalog No.
GM-Tg-hg-T68443-Ab-1,GM-Tg-hg-T68443-Ab-2
Product Name
Anti-MMP-21/MMP21 monoclonal antibody
Format
mab
Target Name
MMP-21
Gene ID
MMP21
Gene Name
MMP21
Gene Alias
HTX7, MMP-21
Protein Sub-location
Secreted Protein/Potential Cytokines
Category of antibody
FACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-MMP-21 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.