Anti-FCG2A/ FCGR2A/ CD32 antibody for FACS & in-vivo assay| GMab

Cat:GM-Tg-hg-T22212-Ab
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$3,090.00

SKU GM-Tg-hg-T22212-Ab Category

Description

Pre-made anti-FCGR2A benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FCGR2A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: FCGR2A, gene name: FCGR2A, also named as CD32, CD32A, CDw32, FCG2, FCGR21, FcGR, IGFR2, FCGR2A. This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].

Antigen Information

Catalog No.

GM-Tg-hg-T22212-Ab-1,GM-Tg-hg-T22212-Ab-2

Product Name

Anti-FCGR2A monoclonal antibody

Format

mab

Target Name

FCGR2A

Gene ID

FCGR2A

Gene Name

FCGR2A

Gene Alias

CD32, CD32A, CDw32, FCG2, FCGR21, FcGR, IGFR2, FCGR2A

Protein Sub-location

Transmembrane Protein

Category of antibody

FACS/Biofunctional Antibody, Therapeutics Target antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-FCGR2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.