Anti-TENX/ TNXB/ EDS3 functional antibody for cell culture, ELISA & in-vivo assay| GMab
Cat:GM-Tg-hg-SE0520-Ab
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
$3,090.00
SKU
GM-Tg-hg-SE0520-Ab
Category Target Antibody
Description
Pre-made anti-TNXB benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TNXB mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: TNXB, gene name: TNXB, also named as EDS3, EDSCLL, EDSCLL1, HXBL, TENX, TN-X, TNX1, TNXB2, TNXBS, VUR8, XB, XBS, TNXB. This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Antigen Information
Catalog No.
GM-Tg-hg-SE0520-Ab-1,GM-Tg-hg-SE0520-Ab-2
Product Name
Anti-TNXB monoclonal antibody
Format
mab
Target Name
TNXB
Gene ID
TNXB
Gene Name
TNXB
Gene Alias
EDS3, EDSCLL, EDSCLL1, HXBL, TENX, TN-X, TNX1, TNXB2, TNXBS, VUR8, XB, XBS, TNXB
Protein Sub-location
Secreted Protein/Potential Cytokines
Category of antibody
FACS/Biofunctional Antibody
Derivation (species)
Mouse
Species Reactivity
Human(H)
CH1+2+3 Isotype (Receptor identification)
IgG
Type of Light Chain (VD-LC)
N/A
Expression platform
Mammalian Expression
Bioactivity validation
Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag
Fc
Products description
Pre-made anti-TNXB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity
Purity: ≥95% (SDS-PAGE)
Application
Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation
Lyophilized from sterile PBS, PH 7.4
Storage
Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.