Anti-TRAT1/ HSPC062/ TCRIM antibody for FACS & in-vivo assay| GMab

Cat:GM-Tg-hg-MP1867-Ab
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$3,090.00

SKU GM-Tg-hg-MP1867-Ab Category

Description

Pre-made anti-TRAT1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TRAT1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. The target: TRAT1, gene name: TRAT1, also named as HSPC062, TCRIM, TRIM, pp29/30. Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream of or within negative regulation of receptor recycling; negative regulation of transport; and positive regulation of signal transduction. Located in centriolar satellite; mitotic spindle; and plasma membrane. Part of T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022].

Antigen Information

Catalog No.

GM-Tg-hg-MP1867-Ab-1,GM-Tg-hg-MP1867-Ab-2

Product Name

Anti-TRAT1 monoclonal antibody

Format

mab

Target Name

TRAT1

Gene ID

TRAT1

Gene Name

TRAT1

Gene Alias

HSPC062, TCRIM, TRIM, pp29/30

Protein Sub-location

Transmembrane Protein

Category of antibody

FACS/Biofunctional Antibody

Derivation (species)

Mouse

Species Reactivity

Human(H)

CH1+2+3 Isotype (Receptor identification)

IgG

Type of Light Chain (VD-LC)

N/A

Expression platform

Mammalian Expression

Bioactivity validation

Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).

Tag

Fc

Products description

Pre-made anti-TRAT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)

Purity

Purity: ≥95% (SDS-PAGE)

Application

Biological drug discovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Formulation

Lyophilized from sterile PBS, PH 7.4

Storage

Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.