Diagnostic antibodies and antigens for food safety testing in mycotoxin and chemical contamination

SOCAIL MEDIA

Competitive immunoassay-validated anti-Hapten (small molecules, chemicals) antibody against hapten (small molecules, chemicals) and hapten-carrier conjugated competitive antigens(Carrier-coupled antigen,immunogen,hapten-carrier conjugates, BSA-conjugated, OVA-conjugated).

The anti-Hapten antibodies against haptens had been validated with our hapten-carrier conjugates via competitive ELISA test.

GeneMedi offers paired anti-small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.) antibodies (monoclonal antibody, mab) and small molecules competitive antigens (Carrier-coupled antigen, immunogen, hapten-carrier conjugates, BSA-conjugated, OVA-conjugated) for the rapid test and diagnostics kit of Growth Promoters, Toxic Heavy Metal, Myotoxins,Nutritions, Food Safety, Pesticides, Drugs of Abuse, Allergen, Antibiotics, Agricultural, Water Contamination and so on.

All our anti-chemicals antibodies and small molecules hapten-carrier conjugates antigens (BSA-conjugated, OVA-conjugated)are suitable for in competitive ELISA, Lateral flow immunoassay (LFIA) and other immunoassays in diagnostics and rapid test kit. The carrier-coupled antigens of small molecules can act as immunogens.

Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. Sulfamethoxazole with trimethoprim is a fixed antibiotic combination that is widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections. Recently, our R&D department demonstrated that our GMP-SMT-73-Ab-1 (Anti-Trimethoprim(TMP) mouse monoclonal antibody) has a large linear range and good sensitivity against the GMP-SMT-73-Ag-1 (BSA-Trimethoprim(TMP)). Below is the result of GeneMedi’s Anti-Trimethoprim(TMP) mouse monoclonal antibody validation with BSA-Trimethoprim(TMP) in ELISA. We highly recommend the Ab&Ag to you.

Figure 1. GeneMedi's GMP-SMT-73-Ab-1 (Anti-Trimethoprim(TMP) mouse monoclonal antibody) is validated to detect the GMP-SMT-73-Ag-1 (BSA-Trimethoprim(TMP)) in ELISA. EC50 = 234.5 ng/ml.

Genemedi supplies Small Molecule Diagnostic for a wide selection of choices (please see below).

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Cat No.
Small molecules (Chemicals, Antibiotics, Mycotoxins, Hormones, Drugs of Abuse, etc.)
Carrier-coupled antigen/immunogen (hapten-carrier conjugates)
Anti-Hapten Antibody
Bioactivity validation
ELISA IC50(ppb)
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Sulfonamides Residue (SAs) (sulfamethoxazole (SMX), 5-atom-rings)
BSA-Sulfonamides Residue (SAs) (sulfamethoxazole (SMX), 5-atom-rings); OVA-Sulfonamides Residue (SAs) (sulfamethoxazole (SMX), 5-atom-rings)
Anti-Sulfonamides Residue (SAs) (sulfamethoxazole (SMX), 5-atom-rings) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
2-5
Chloramphenicol (TAP )
BSA-Chloramphenicol (TAP ); OVA-Chloramphenicol (TAP )
Anti-Chloramphenicol (TAP ) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
0.2-0.3
Acetamiprid(AAP)
BSA-Acetamiprid(AAP); OVA-Acetamiprid(AAP)
Anti-Acetamiprid(AAP) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
2-3
Nitenpyram(NIT)
BSA-Nitenpyram(NIT); OVA-Nitenpyram(NIT)
Anti-Nitenpyram(NIT) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
2-3
Carbofuran(CAR)
BSA-Carbofuran(CAR); OVA-Carbofuran(CAR)
Anti-Carbofuran(CAR) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
0.1-0.3
Aldicarb(ADC)
BSA-Aldicarb(ADC); OVA-Aldicarb(ADC)
Anti-Aldicarb(ADC) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
0.1-0.3
Fenpropathrin(FPP)
BSA-Fenpropathrin(FPP); OVA-Fenpropathrin(FPP)
Anti-Fenpropathrin(FPP) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
3-5
Isoprocarb
BSA-Isoprocarb; OVA-Isoprocarb
Anti-Isoprocarb mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
1-2
Fipronil 
BSA-Fipronil ; OVA-Fipronil 
Anti-Fipronil  mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
0.60
2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
BSA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T); OVA-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T)
Anti-2,4,5-Trichlorophenoxyacetic acid(2,4,5-T) mouse monoclonal antibody
Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
3-5
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Antibiotics

Diagnostic antibodies and antigens for the detection of maximum residue limit(MRL) of antibiotics

Antibiotics are used for veterinary purposes almost as soon as they had been developed for human medicine. They are supplemented in the animal feed for growth promotion and treatment of infections, which are important during the development of intensive methods of animal husbandry, as a result there are major hazards that could be posed by antibiotic residues in foods like raw milk, poultry, cattle, p0rcine, fish and so on. The possible presence of antimicrobial residues (AR) in farm foods poses a risk for consumers such as allergic reactions, toxicity, carcinogenic effects, selection of resistant bacteria, disruption of human normal flora, provoke immunological response and inhibition of the starter culture.

The risk of residue from these foods are higher in developing countries compared to developed one. This might be related with lack of facilities for detection and regulatory bodies that control the drug residues level in foods in the form of maximum residue limits (MRLs). Therefore, to prevent/minimize the risk of antimicrobial residue in milk, different methods of detection of residue to the standard limits level in all food items is possible by chemical methods, microbiological methods and immunological assays. However, Genemedi developed the antigen and antibody to detect the MRL of various antibiotics in the food such as raw milk, poultry, cattle, p0rcine, fish and so on. Detecting the MRL of different antibiotics from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.