Category Archives: lc3

AAV-LC3 production service for Autophagy Flux Detection

customized AAV production Customize Option Autophagy Flux detection vector GM-AAVPAU01: AAV-CMV-mRFP-GFP-LC3GM-AAVPAU02: AAV-CMV-GFP-LC3 AAV Packaging Serotype AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant (AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro, AAV-PHP.B, AAV-PHP.eB, AAV-PHPS, […]

Lentivirus-LC3 production service for Autophagy Flux Detection

Customized Lentivirus production Introduction to AAV-LC3 production service for Autophagy Flux Detection Premade LC3 Autophagy Biosensors Products and user manual Adeno associated virus(AAV) AAV-GFP-LC3 Autophagy Biosensor AAV-mRFP-GFP-LC3 Autophagy Biosensor Adenovirus Adv-GFP-LC3 Autophagy Biosensor Adv-mRFP-GFP-LC3 Autophagy Biosensor Lentivirus Lv-GFP-LC3 Autophagy Biosensor Lv-mRFP-GFP-LC3 Autophagy Biosensor LC3 Autophagy Biosensors User Manual AAV-LC3 User Manual    Adenovirus-LC3 User Manual  […]

Publication-Autophagy

Selected Publications using Genemed’s Autophagy Products/Services Publications Link to the article Products/Services T. Yu et.al, ‘Fusobacterium Nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy’, Cell, 170 (2017), 548-63 e16. http://www.ncbi.nlm.nih.gov/pubmed/28753429 Autophagy flux RFP-GFP-LC3 biosensor M. Liu et.al, ‘Sirt6 Deficiency Exacerbates Podocyte Injury and Proteinuria through Targeting Notch Signaling’, Nat Commun, 8 (2017), 413. http://www.ncbi.nlm.nih.gov/pubmed/28871079 […]

Autophagy Biosensors

Introduction-LC3 Autophagy Biosensors Autophagy is a highly regulated homeostatic degradative process where cells destroy their own components via the lysosomal machinery and recycle them. This process plays both protective and deleterious roles in many diseases, including Alzheimer’s disease, aging, cancer, infection and Crohn’s disease. Elucidating the correlation between autophagy and apoptotic cell death has become […]