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Pre-made Oregovomab benchmark antibody (Whole mAb, anti-MUC16 therapeutic antibody, Anti-CA125 Antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-INN-940
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Product Details
Anti-MUC16 therapeutic antibody (Pre-made Oregovomab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Oregovomab (marketed under the trade name OvaRex) is a mouse monoclonal antibody it binds to the antigen CA125, a carbohydrate antigen. It is designed for the treatment of ovarian cancer.[1]
| Products Name (INN Index) | Pre-Made Oregovomab Biosimilar, Whole Mab, Anti-Muc16 Antibody: Anti-CA125 therapeutic antibody |
|---|---|
| INN Name | oregovomab |
| Target | MUC16 |
| Format | Whole mAb |
| Derivation | Mus musculus |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 – kappa |
| VD LC | IgG1 – kappa |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | AltaRex?Corp. (Edmonton AB Canada) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | MUC16 |
| Package |
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