Pre-Made Epoetin Alfa biosimilar, Recombinant Protein: Recombinant EPO(erythropoietin) therapeutic protein targeting EPOR for drug discovery and mechanism of action (MOA) research

Cat:GMP-Bios-INN-840

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SKU GMP-Bios-INN-840 Category Tag

Product Details

Pre-Made Epoetin Alfa biosimilar, Recombinant Protein: Recombinant EPO(erythropoietin) therapeutic protein targeting EPOR is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Epoetin alfa is a human erythropoietin produced in cell culture using recombinant DNA technology.[3] Authorised by the European Medicines Agency on 28 August 27, it stimulates erythropoiesis (increasing red blood cell levels) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy.

Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow. Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of patients with anemia associated with various clinical conditions, such as chronic renal failure, antiviral drug therapy, chemotherapy, or a high risk for perioperative blood loss from surgical procedures

Products Name (INN Index)

Pre-Made Epoetin Alfa biosimilar, Recombinant Protein: Recombinant EPO(erythropoietin) therapeutic protein targeting EPOR Pre-made [INN Name] biosimilar, [Format] targeting [Target1/Target2]), recom

INN Name

epoetin alfa

Target

EPOR

Format

Recombinant Protein

Derivation

Human

Species Reactivity

Human

CH1 Isotype

EPO

VD LC

EPO

Highest_Clin_Trial (Jan '20)

NA

Est. Status

NA

100% SI Structure

NA

99% SI Structure

NA

95-98% SI Structure

NA

Year Proposed

NA

Companies

Centocor?Ortho Biotech?Products?LP (Raritan NJ USA) / Amgen (Thousand Oaks CA USA)

Conditions Approved

NA

Conditions Active

NA

Conditions Discontinued

NA

Development Tech

NA

Previous Name

NA

Gm Offical Target Name

EPOR

Package

, ,

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