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Pre-made Edobacomab benchmark antibody (Whole mAb, anti-endotoxin (lipid A, domain of lipopolyaccharide, LPS) [gram negative bacteria]/endotoxin therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat:GMP-Bios-INN-808
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Product Details
Anti-endotoxin (lipid A, domain of lipopolyaccharide, LPS) [gram negative bacteria]/endotoxin therapeutic antibody (Pre-made Edobacomab biosimilar, Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Edobacomab, codenamed E5, is a mouse monoclonal antibody that was investigated as a possible treatment for sepsis caused by Gram-negative bacterial infections.
| Products Name (INN Index) | Pre-Made Edobacomab Biosimilar, Whole Mab: Anti-Endotoxin (Lipid A, Domain Of Lipopolyaccharide, Lps) [Gram Negative Bacteria] therapeutic antibody |
|---|---|
| INN Name | edobacomab |
| Target | endotoxin (lipid A, domain of lipopolyaccharide, LPS) [gram negative bacteria] |
| Format | Whole mAb |
| Derivation | Mus musculus |
| Species Reactivity | Human |
| CH1 Isotype | IgM – nd |
| VD LC | IgM – nd |
| Highest_Clin_Trial (Jan '20) | NA |
| Est. Status | NA |
| 100% SI Structure | NA |
| 99% SI Structure | NA |
| 95-98% SI Structure | NA |
| Year Proposed | NA |
| Year Recommended | NA |
| Companies | Xoma (Berkeley CA USA) / Pfizer (New York NY USA) |
| Conditions Approved | NA |
| Conditions Active | NA |
| Conditions Discontinued | NA |
| Development Tech | NA |
| Previous Name | NA |
| Gm Offical Target Name | endotoxin (lipid A, domain of lipopolyaccharide, LPS) [gram negative bacteria] |
| Package |
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